Key result
Surgery and chemotherapy fail to prevent early death in cardiac malignant fibrous histiocytoma.
Why the study?
Primary cardiac malignant fibrous histiocytoma is a rare tumor with limited reported cases and uncommon pericardial involvement.
Case Report (n=1)
This case report highlights a rare presentation of primary cardiac malignant fibrous histiocytoma with pericardial involvement, diagnosed via echocardiography.
Echocardiography aids detection of rare primary cardiac tumors; extends sparse case series on malignant fibrous histiocytoma but leaves management unresolved.
We present the case of a 53 years-old woman presenting with congestive heart failure and pleural and pericardial effusions, in whom transthoracic and transesophageal echocardiography revealed multilocular cardiac tumor involving the left atrium wall, extending into the pericardium. Tumor was excised surgically and proved to be a malignant fibrous histiocytoma, primarily confined to the heart. Despite surgery followed by chemotherapy, the patient died a few months later. This is the 47th case of primary cardiac fibrous malignant histiocytoma reported in the literature. The pericardial involvement has been only rarely reported. Echocardiography was the method of diagnosis before rapid referral to surgery.
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Dorobanţu et al. (2004) conducted a case report in Primary left heart malignant fibrous histiocytoma (n=1). Surgical excision and chemotherapy was evaluated on Clinical outcome. Surgical excision followed by chemotherapy for a primary cardiac malignant fibrous histiocytoma in a 53-year-old woman did not prevent death a few months later.
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