Key result
Repeated resection and chemotherapy fail to prevent relapse in primary cardiac malignant fibrous histiocytoma.
Why the study?
Malignant fibrous histiocytoma is an extremely rare primary malignant tumor of the heart with poor prognosis and limited reported cases.
Case Report (n=1)
Highlights a rare case of primary cardiac malignant fibrous histiocytoma with poor prognosis despite surgical resection and chemotherapy.
Authors
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Cardiac MFH carries high relapse risk despite multimodal therapy; extends sparse case literature but leaves optimal strategies unresolved.
Miličić et al. (2007) conducted a case report in Primary malignant fibrous histiocytoma of the heart (n=1). Surgical resection and chemotherapy was evaluated on Tumor recurrence and metastasis. A 58-year-old woman with primary cardiac malignant fibrous histiocytoma experienced local tumor relapse and skeletal muscle metastases despite repeated surgical resections and multiple lines of chemotherapy.
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