Metformin‐Associated Lactic Acidosis in an Older Adult After Colonoscopy: An Uncommon Trigger for a Rare Complication

Warfarin-induced skin necrosis was found to be associated with heparin-induced thrombocytopenia, and protein C or S or antithrombin III hereditary deficiencies.These coagulation disorders seem to emphasize or accelerate skin necrosis but are not at the origin of the necrosis process.10 CONCLUSION Warfarin-induced skin necrosis is a well-known but rare pathology, especially at 84 years old.Such large skin necrosis as in the current case is rarely described, and necrosis of the scrotum and testicles has never been reported.With no coagulation protein deficiency or tumoral process, the precise pathological pathway was not clear in the current case.Clinical presentation was the same as described in literature.Because warfarin is widely used in elderly adults, geriatricians must know about such severe complications of its use with regard to their potential severe outcomes.After surgical treatment and warfarin withdrawal, the man survived despite multiple amputations.