Estimating constituents of optical isomers in mixed solution based on spin Hall effect of light

In this paper, an optical method for precisely estimating constituents of optical isomers (OIs) in mixed solution is presented. We convert the composition ratio of OI into polarization-rotation-dependent spin Hall effect of light (SHEL). The theoretical model between the SHEL and OI composition ratio is established in the geometrical-optics picture, and the spatial shift can be measured through weak measurement technique. Based on our theory, the concentrations of glucose and fructose in a mixed solution are separately obtained. Our accurate measurements of the chiral enantiomer composition can provide an avenue for chiral drug synthesis and analysis.