Key result
Moderate intensity cycling significantly reduced pain intensity ratings (MD 2.0) and increased brain activity in regions involved in pain modulation compared to quiet rest in women with fibromyalgia.
Why the study?
Does exercise improve central nervous system modulation of pain in female patients with fibromyalgia?
RCT (n=24)
Open-label
Randomized and counterbalanced
No
Does exercise improve central nervous system modulation of pain in female patients with fibromyalgia?
Mean Difference: 2 (95% CI 0.9–5)
Absolute Event Rate: 9.31% vs 11.33%
p-value: p=<0.05
Exercise may benefit patients with fibromyalgia by improving the functional capacity of the central nervous system's pain modulatory system.
No takes yet. Share an insight, caveat, or question.
May reduce acute pain via central modulation in fibromyalgia; hypothesis-generating for exercise prescriptions, pending larger trials.
Ellingson et al. (2016) conducted an RCT in Fibromyalgia (n=24). Moderate intensity cycling vs. Quiet rest was evaluated on Pain intensity ratings to noxious heat stimuli (first run) (MD 2.0, 95% CI 0.9-5.0, p=<0.05). Moderate intensity cycling significantly reduced pain intensity ratings (MD 2.0) and increased brain activity in regions involved in pain modulation compared to quiet rest in women with fibromyalgia.
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