What does this research mean for the field?

Patients undergoing gastrointestinal surgery in low-HDI countries have a substantially higher 30-day incidence of surgical site infection (23.2%) compared to those in high-HDI countries (9.4%). Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.SUPPORTS_CONSENSUS.

February 13, 2018The Lancet Infectious DiseasesOpen Access

Surgical site infection—the next frontier in global surgery

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Elective or emergent gastrointestinal resection. Intervention: Low Human Development Index (HDI) vs. High Human Development Index (HDI). Primary outcome: Surgical site infection (SSI) incidence within 30 days after surgery.

View Full Paper

Ask AI

Bookmark

Key result

Living in a low-HDI country was associated with a 23.2% 30-day incidence of surgical site infection following gastrointestinal resection, compared to 9.4% in high-HDI countries.

Population

Consecutive patients undergoing elective or emergent gastrointestinal resection across 343 centres in 66…

Design

Editorial

Follow-up

30 days

Authors

RSRobert G. SawyerFlorida State University HEHeather L. EvansCollege of Charleston

Discussion

Member takes

Implication

Surgical site infections after gastrointestinal surgery pose a major global burden, with disproportionately higher rates in low-HDI countries, emphasizing the need for improved infection prevention protocols and antimicrobial stewardship.

Study Design

Type

Cohort

Multicenter

Yes

Structured PICO

Population

Patients undergoing clean-contaminated, contaminated, and dirty elective or emergent gastrointestinal resection across 343 centres in 66 countries, followed for 30 days.

Outcome

SSI incidence within 30 days after surgeryhard clinical

Main Result

Absolute Event Rate: 23.2% vs 9.4%

Limitations

Data are not granular enough to assess adherence to accepted practice for antimicrobial prophylaxis.
In-person, 30-day follow-up was not feasible across the entire cohort.
Substantial reliance on post-discharge telephone reporting is problematic because patients are unreliable for discernment of SSI.
Unclear whether variance in cultural norms and post-operative patient education between countries and HDI strata affects the detection of SSI.
Data not granular enough to assess adherence to accepted practice for antimicrobial prophylaxis
In-person, 30-day follow-up was not feasible across the entire cohort
Substantial reliance on post-discharge telephone reporting is problematic because patients are unreliable for discernment of SSI

Cite This Study

Sawyer et al. (2018) conducted a cohort in Elective or emergent gastrointestinal resection. Low Human Development Index (HDI) vs. High Human Development Index (HDI) was evaluated on Surgical site infection (SSI) incidence within 30 days after surgery. Living in a low-HDI country was associated with a 23.2% 30-day incidence of surgical site infection following gastrointestinal resection, compared to 9.4% in high-HDI countries.

synapsesocial.com/papers/6ab70e66ed6a4447fcebb5f0 https://doi.org/10.1016/s1473-3099(18)30118-x

View Full Paper

Ask AI

Bookmark

Surgical site infection—the next frontier in global surgery

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Surgical site infection—the next frontier in global surgery

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Also Consider