Key result
Pregnancy in a patient with Budd-Chiari syndrome resulted in a lethal outcome within 2 years after delivery, underscoring the need for multidisciplinary care and preconception risk classification.
Why the study?
What is the effect of pregnancy on Budd-Chiari syndrome and how should risk be classified?
Case Report (n=1)
What is the effect of pregnancy on Budd-Chiari syndrome and how should risk be classified?
Pregnancy in Budd-Chiari syndrome carries significant risks, highlighting the need for multidisciplinary management and risk classification for preconception counseling.
Suggests high maternal risk; case reports leave open need for validated preconception stratification.
Due to its rarity, experience with pregnancy in Budd-Chiari syndrome (BCS) is limited. With the advent of new treatment modalities, transjugular intrahepatic portosystemic shunt in particular, numbers of affected women seeking pregnancy with BCS are expected to rise. Here, we use a case that ended lethal within 2 years after delivery to discuss the effect of pregnancy on BCS and vice versa, and to highlight the necessity of a multidisciplinary teamwork. Additionally, a risk classification is proposed which may serve as a framework for preconception counseling and assist in the establishment and evaluation of treatment algorithms; its criteria need to be defined and assessed for their applicability in further studies.
No takes yet. Share an insight, caveat, or question.
Merz et al. (2016) conducted a case report in Budd-Chiari syndrome in pregnancy (n=1). Pregnancy was evaluated on Maternal mortality. Pregnancy in a patient with Budd-Chiari syndrome resulted in a lethal outcome within 2 years after delivery, underscoring the need for multidisciplinary care and preconception risk classification.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: