Key result
Acute hepatitis E infection preceded Guillain-Barré syndrome in a European patient, with antiganglioside GM2 antibodies suggesting molecular mimicry as the underlying mechanism.
Population
A European individual with Guillain-Barré syndrome following acute hepatitis E
Design
Case_report
Authors
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Raises awareness for hepatitis E testing in Guillain-Barré syndrome; hypothesis-generating for molecular mimicry and requires larger studies.
Case Report (n=1)
This case report suggests that molecular mimicry involving ganglioside GM2 may play a role in the pathogenesis of Guillain-Barré syndrome triggered by acute hepatitis E.
Loly et al. (2009) conducted a case report in Guillain-Barré syndrome following acute hepatitis E (n=1). Acute hepatitis E infection was evaluated on Development of Guillain-Barré syndrome and presence of antiganglioside GM2 antibodies. Acute hepatitis E infection preceded Guillain-Barré syndrome in a European patient, with antiganglioside GM2 antibodies suggesting molecular mimicry as the underlying mechanism.
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