Key result
The Osteoporosis Self-Assessment Tool score at a cutoff of 7.5 detected osteoporosis risk with an area under the curve of 71% (P<0.000), 71% sensitivity, and 59% specificity.
Why the study?
Does the Osteoporosis Self-Assessment Tool (OST) score accurately detect osteoporosis compared to DEXA in premenopausal Egyptian women?
Cross-Sectional (n=539)
No
Does the Osteoporosis Self-Assessment Tool (OST) score accurately detect osteoporosis compared to DEXA in premenopausal Egyptian women?
Effect estimate: AUC 71%
p-value: p=<0.000
An OST score cutoff of 7.5 provides moderate diagnostic accuracy (AUC 71%) for detecting osteoporosis risk in premenopausal Egyptian women.
Background Osteoporosis, chronic diseases, or conditions that may start early in the premenopausal period have become a real well-being medical issue worldwide.Aim The aim was to assess the accuracy of Osteoporosis Self-Assessment Tool (OST) score as a screening method for detection of osteoporosis among Egyptian premenopausal women compared with dual-energy radiographic absorptiometry.Participant and methods This was a retrospective cross-section study including 539 premenopausal Egyptian women, and their age ranged from 20 to 44 years. They underwent evaluation by dual-energy X-Ray absorptiometry examination of the left femoral neck at the ‘Bone Densitometry Unit’ of the ‘Medical Excellence Research Center (MERC)’, ‘National Research Centre (NRC)’, and then BMI and OST score were calculated from the data.Results The cutoff value of OST among premenopausal women was 7.5 to detect the risk of osteoporosis using the receiver operating characteristic curve, with 71% area under the curve (P<0.000), 71% sensitivity, 59% specificity, 65% accuracy, 63% positive predictive value, and 67% negative predictive value. Any form of bone loss ‘osteopenia or osteoporosis’ could be suspected if there is decreased BMI in the presence of risk factors.Conclusion The Egyptian premenopausal women OST score is 7.5. If it is lower this value, osteoporosis will be predict and needs further management..
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Sherity et al. (2020) conducted a cross-sectional in Osteoporosis (n=539). Osteoporosis Self-Assessment Tool (OST) score vs. Dual-energy X-Ray absorptiometry was evaluated on Detection of osteoporosis risk (AUC 71%, p=<0.000). The Osteoporosis Self-Assessment Tool score at a cutoff of 7.5 detected osteoporosis risk with an area under the curve of 71% (P<0.000), 71% sensitivity, and 59% specificity.
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