Key result
Cognitive impairment in severe mental disorders is linked to significantly higher vascular burden.
Why the study?
The relationship between cognitive impairment and vascular burden in patients with severe mental disorder is less consistent and underexplored.
Is cognitive impairment associated with increased vascular burden in patients with severe mental disorder?
Cross-Sectional (n=60)
No
Is cognitive impairment associated with increased vascular burden in patients with severe mental disorder?
p-value: p=<0.05
Cognitive impairment is associated with higher vascular burden in patients with severe mental disorders, highlighting the need for targeted cardiovascular risk evaluation and adapted psychoeducation in this population.
Supports vascular screening in severe mental illness with cognitive impairment; hypothesis-generating and should not yet change practice.
Introduction: Cognitive impairment is related to an increase in cardiovascular risk (CVR) in the general population. However, in severe mental disorder (SMD), the evidence is less consistent. Few studies have evaluated the relationship between cognition and vascular burden in SMD. This study determines the relationship between cognition and vascular burden in patients with SMD.Methods: Sixty SMD patients (61% men, mean age: 46) attending a psychosocial rehabilitation centre were included. We evaluated sociodemographic, clinical, laboratory, quality of life and functionality characteristics. And we analysed the association between cognitive performance and vascular burden.Results: SMD diagnoses were: 41.7% schizophrenia, 20.0% bipolar, 5.0% schizoaffective, 21.7% depressive and 11.7% other. Cognitive impairment was present in 55% of the cases. The average vascular burden was 3.2. Patients with cognitive impairment have a significantly higher vascular burden than patients without cognitive impairment (p < 0.05). The speed of processing had a moderate correlation with vascular burden (r = −0.457, p = 0.001).Conclusions: Patients with cognitive impairment had a significantly higher vascular burden than patients without cognitive impairment. There are two practical clinical implications: CVR should be evaluated in all SMD patients; and psychoeducation programmes for CVR should be performed and adapted to the cognitive deficits.
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Boreu et al. (2019) conducted a cross-sectional in Severe mental disorder (n=60). Cognitive impairment vs. No cognitive impairment was evaluated on Vascular burden (p=<0.05). Cognitive impairment in patients with severe mental disorder was associated with a significantly higher vascular burden compared to those without cognitive impairment (p < 0.05).
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