Three new shionane-type triterpenes, shion-22-methoxy-20(21)-en-3-one (1), shion-22(30)-en- 3,21-dione (2), shion-22-methoxy-20(21)-en-3β -ol (3), were isolated from the rhizomes of Aster tataricus. Their structures have been determined on the basis of MS, IR, 1D and 2D NMR spectral evidences. Compounds 1 and 2 show inhibitory activities on HBsAg with IC50 values of 0.89 and 4.49 μgmL−1, respectively, 1 shows inhibitory activity on HBeAg with an IC50 value of 0.83 μgmL−1, and 2 shows inhibitory activity on HA with an IC50 value of 11.18 μgmL−1.
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Zhou et al. (2010) studied this question.
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