Key result
Mechanical thrombectomy successfully treats tPA-refractory ischemic stroke caused by cardiac myxoma embolus.
Why the study?
Cardiac tumor is a rare cause of cerebral embolic infarction with no established therapeutic strategies, and some tumorous emboli do not respond to rt-PA.
Case Report (n=1)
Emergency mechanical thrombectomy using a Merci Retriever is a viable option for treating acute ischemic stroke caused by cardiac myxoma emboli unresponsive to rt-PA.
May support thrombectomy for rt-PA-refractory tumor emboli; hypothesis-generating and requires prospective validation before practice change.
Cardiac tumor is a rare cause of cerebral embolic infarction which has no established therapeutic strategies. Although some cases were successfully treated by recombinant tissue-plasminogen activator (rt-PA), this article indicates the effectiveness of emergency mechanical thrombectomy for tumorous type of emboli which do not respond to rt-PA. A 34-year-old man presented with ischemic stroke and right middle cerebral artery (MCA) occlusion by cardiac tumor originating emboli. Intravenous rt-PA therapy was ineffective, but mechanical endovascular thrombectomy using Merci Retriever was successful. His neurological deficit began to improve and good outcome was obtained at discharge. The embolus was histologically identical to a cardiac myxoma, confirmed and treated successfully by surgery later. We report the first successfully treated tumorous embolic stroke case with cardiac tumor by using Merci Retriever. Emergency mechanical thrombectomy would be an option for elastic hard myxoma emboli.
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Ryu et al. (2015) conducted a case report in Ischemic stroke and right middle cerebral artery occlusion by cardiac tumor originating emboli (n=1). Mechanical endovascular thrombectomy using Merci Retriever was evaluated on Neurological improvement and outcome at discharge. Mechanical endovascular thrombectomy using a Merci Retriever successfully treated a 34-year-old man with an ischemic stroke caused by a cardiac myxoma embolus unresponsive to rt-PA.
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