Key result
QX-572 terminates perioperative cardiac arrhythmias in 26 patients but enhances neuromuscular blockade.
Why the study?
QX-572's antiarrhythmic activity and neuromuscular effects in humans required evaluation to guide further clinical trials.
Does QX-572 treat cardiac arrhythmias developing during anesthesia and operation?
Population
26 patients with cardiac arrhythmias during anesthesia and operation
Comparison
QX-572 treatment with no direct comparator
Design
Observational case series
Authors
Loading...
May aid intraoperative arrhythmia management; leaves open efficacy and safety pending randomized trials.
Observational (n=26)
Does QX-572 treat cardiac arrhythmias developing during anesthesia and operation?
QX-572 demonstrates significant antiarrhythmic activity in patients developing arrhythmias during anesthesia, though it potentiates certain neuromuscular blockers and can cause tachycardia.
Ronald L. Katz (1965) conducted an observational in Cardiac arrhythmias during anesthesia and operation (n=26). QX-572 was evaluated on Successful treatment of cardiac arrhythmias. QX-572 successfully treated cardiac arrhythmias in 26 patients during anesthesia and operation, though it increased the neuromuscular blocking action of succinylcholine and d-tubocurare.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: