Key result
Simultaneous surgical treatment of abdominal aortic aneurysms and clean-contaminated abdominal diseases resulted in a 5.8% mortality rate, which was significantly higher than the 0% mortality observed when treating clean wound diseases simultaneously.
Why the study?
Patients with abdominal aortic aneurysm frequently have coexisting abdominal surgical diseases, but optimal timing and approach for simultaneous treatment remain unclear.
Does simultaneous surgical treatment of coexisting abdominal diseases during abdominal aortic aneurysm repair improve clinical outcomes compared to staged treatment?
Cohort (n=327)
No
Does simultaneous surgical treatment of coexisting abdominal diseases during abdominal aortic aneurysm repair improve clinical outcomes compared to staged treatment?
Absolute Event Rate: 5.8% vs 0%
p-value: p=<0.05
Simultaneous correction of coexisting abdominal diseases during open AAA repair is safe for clean wounds, but should be restricted to selected cases for clean-contaminated wounds, with EVAR serving as a valid alternative.
Patients with abdominal aortic aneurysm (AAA) frequently have other abdominal pathologies of surgical interest (other diseases, OD). Out of 1,375 elective open aortic replacements for AAA, 315 cases with OD were subdivided in Group 1 (82 patients with "clean wound" OD) and Group 2 (233 patients with "clean-contaminated wound" OD). The results of the sub-groups in which OD was treated at the same time as AAA were analysed (1a, 66 cases and 2a, 86 cases) and compared with OD not treated at the same time as AAA (1b, 16 cases and 2b, 147 cases). EVAR was done in 12 patients with a infrarenal AAA and concomitant abdominal disease. In this group post-operative complications occurred in two patients (endoleaks) and no sign of endograft infection was developed. Mean follow-up was 36 months. Mortality was 0% in Group 1a, 1b, 2b and 5.8% in Group 2a. In Group 1a there were one haemoperitoneum, one ischaemic colitis and one graft infection. In Group 1b there were 4 nefrectomies for renal carcinoma and three emergency hernia repairs within 18 months from AAA operation. In Group 2a the follow-up was uneventful. In Group 2b there was no acute complication of OD and 57.2% of patients were subsequently operated for OD. In the EVAR group the 30-day and late mortality rates were 0 and 25%, respectively and all deaths were cancer-related. Contemporary correction of OD in open surgery for AAA should be performed in clean wound cases, while clean-contaminated operations can be done only in selected cases. EVAR is a valid alternative technique to open vascular surgery for the concomitant treatment of aortic aneurysms and abdominal pathologies.
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Bonardelli et al. (2012) conducted a cohort in Abdominal aortic aneurysm with coexisting surgical abdominal diseases (n=327). Simultaneous surgical treatment of AAA and clean-contaminated abdominal diseases vs. Simultaneous surgical treatment of AAA and clean wound abdominal diseases was evaluated on Mortality (p=<0.05). Simultaneous surgical treatment of abdominal aortic aneurysms and clean-contaminated abdominal diseases resulted in a 5.8% mortality rate, which was significantly higher than the 0% mortality observed when treating clean wound diseases simultaneously.
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