Malignant circumscribed acral hypokeratosis

Circumscribed acral hypokeratosis (CAH) is a rarely reported, idiopathic condition typically identified as a well-demarcated, depressed patch of erythematous skin, most commonly affecting the palmar aspect of the hand and, rarely, the plantar surface of the foot. The first report of CAH in the literature was in 2002 by Pérez et al.1 It is identified by its distinct clinical and histopathologic features. It has a predilection for middle-aged to elderly women, and the lesion is most often solitary, long-standing, and asymptomatic.