Key result
Phase II cardiac rehabilitation is linked to ~44% lower PHQ-9 depression scores across all groups.
Why the study?
The effect of phase II cardiac rehabilitation on clinical depression in patients with cardiovascular disease is understudied.
Does phase II cardiac rehabilitation improve depression metrics in cardiac patients?
Observational (n=27,670)
Does phase II cardiac rehabilitation improve depression metrics in cardiac patients?
Phase II cardiac rehabilitation is associated with significant improvements in self-reported depression scores across diverse demographic groups.
Cardiovascular disease remains a leading cause of morbidity and mortality, a fact that is commonly associated with co-morbidities such as clinical depression. While phase II cardiac rehabilitation is an established intervention for those with cardiovascular disease, its effect on patients who also suffer from depression are under studied. Aim: To quantify Pre- and Post-cardiac rehabilitation questionnaire scores collected from a large patient data registry. For this investigation, 27 670 patients completed Patient Health Questionnaire-9 questionnaires both Pre- and Post-rehabilitation (averaging [28.0 ± 8.7] phase II sessions). Findings reveal that questionnaire scores decreased by 40%-48% across all groups, a finding that was independent of assigned sex, race, and ethnicity. Moreover, when data were stratified for questionnaire scores that may indicate major and minor depressive disorder, phase II cardiac rehabilitation outcomes were lower by 61% and 49% respectively. While all groups exhibited lower questionnaire scores following cardiac rehabilitation participation, numerical differences at Pre- and Post-rehabilitation time points indicate that males and White patients have more favorable scores. This latter observation, while not confirmed currently, appears to be linked to referral rates to phase II cardiac rehabilitation, which remain poor for females, racial and ethnic minorities.
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Quindry et al. (2023) conducted an observational in Cardiovascular disease (n=27,670). Phase II cardiac rehabilitation vs. Pre-rehabilitation (baseline) was evaluated on Change in Patient Health Questionnaire-9 (PHQ-9) scores (40%-48% decrease). Phase II cardiac rehabilitation was associated with a 40% to 48% decrease in Patient Health Questionnaire-9 depression scores across all groups.
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