Key result
Cardiovascular lesions underlie ~29% of sudden deaths at autopsy, driven overwhelmingly by CAD.
Why the study?
Sudden cardiac death is a common non-communicable disease and an important mode of death worldwide, requiring accurate diagnosis of its causes through autopsy.
Observational (n=260)
No
Coronary artery disease remains the most frequent cause of sudden cardiac death in autopsy findings, with a strong male predominance and significant involvement of younger patients.
CAD predominates in sudden death autopsies; leaves open prospective studies on prevention in younger males.
In the present era there is a transition of the cause of death from communicable to non-communicable diseases (NCD) due to changing life style as well as environmental factors.Sudden cardiac death (SCD) is one of the most common NCD and an important mode of death all over the world.Hence, the accurate diagnosis of the causes of SCD is now of particular importance.Pathologists are solely responsible for determining the precise cause and mechanism of sudden death through autopsy.In present study we included 260 cases with age ranging from 1 to 80 years.75 (28.8%) of these 260 cases showed cardiovascular lesions with a male: female ratio of 14:1.Coronary artery disease with or without other associated lesions was the most frequent finding (90.7%).Other causes included atherosclerosis of aorta, myocardial infarction (MI), myocarditis and cardiomyopathy.Rare findings were left atrial myxoma and malignant mesothelioma.Though predominantly affected age group was 41-50 years, there was significant number of affected young patients as well.Thus, this study highlights the importance of screening the population from young age itself for cardiovascular diseases to reduce related morbidity and mortality.
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Patil et al. (2021) conducted an observational in Sudden cardiac death (n=260). Autopsy evaluation for cardiovascular lesions was evaluated on Presence of cardiovascular lesions. Autopsy evaluation of 260 sudden death victims revealed cardiovascular lesions in 28.8% of cases, with coronary artery disease being the most frequent finding (90.7%).
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