Key result
Alzheimer's Quick Test color-form naming showed 97% sensitivity and 97% specificity for Alzheimer's disease, versus 84% sensitivity and 100% specificity for the Mini-Mental State Examination.
Why the study?
Does Alzheimer's Quick Test color-form naming provide better diagnostic sensitivity than the Mini-Mental State Examination in adults with Alzheimer's disease?
Case-Control (n=76)
Does Alzheimer's Quick Test color-form naming provide better diagnostic sensitivity than the Mini-Mental State Examination in adults with Alzheimer's disease?
The Alzheimer's Quick Test color-form naming shows high sensitivity and specificity, supporting its potential utility as a screening test for cognitive speed reductions in Alzheimer's disease.
May aid Alzheimer's screening in select settings; leaves open prospective validation before routine adoption.
Performances on Alzheimer's Quick Test color-form naming and Mini-Mental State Examination were compared for 38 adults with Alzheimer's disease and 38 age- and sex-matched normal controls. Group means differed significantly and indicated longer naming times by adults with Alzheimer's disease. The specificity for AQT color-form naming was 97% and sensitivity 97%, i.e., 3% false negatives. The specificity for Mini-Mental State Examination was 100% and sensitivity 84%, i.e., 16% false negatives. These findings, while supporting AQT color-form naming as a screening test for reductions in cognitive speed associated with Alzheimer's disease, are preliminary given the relatively small sample.
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Nielsen et al. (2004) conducted a case-control in Alzheimer's disease (n=76). Alzheimer's Quick Test color-form naming vs. Mini-Mental State Examination was evaluated on Sensitivity and specificity for Alzheimer's disease. Alzheimer's Quick Test color-form naming showed 97% sensitivity and 97% specificity for Alzheimer's disease, versus 84% sensitivity and 100% specificity for the Mini-Mental State Examination.
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