Key result
3D cardiac CT reconstruction reliably estimates pulmonary arterial compliance and pulse wave velocity in stroke-related AF.
Why the study?
Arterial stiffness is a key diagnostic and prognostic feature in cardiovascular diseases, but methods to estimate pulmonary arterial compliance and pulse wave velocity using cardiac CT images in cerebral-cardiovascular patients are needed.
Does an in-house 3D reconstruction algorithm using cardiac CT images allow estimation of pulmonary arterial compliance and pulse wave velocity in patients with stroke and atrial fibrillation?
Observational (n=9)
Does an in-house 3D reconstruction algorithm using cardiac CT images allow estimation of pulmonary arterial compliance and pulse wave velocity in patients with stroke and atrial fibrillation?
A 3D reconstruction algorithm using cardiac CT images can estimate pulmonary arterial compliance and pulse wave velocity to evaluate arterial stiffness.
CT-based pulmonary AC/PWV estimation may aid noninvasive assessment in cerebral-cardiovascular patients; leaves open validation against reference standards.
Arterial stiffness has been proven to be one of the most promising diagnostic and prognostic features of many cardiovascular diseases (CVD). Arterial compliance (AC) and pulse wave velocity (PWV) allows a good quantitative assessment of arterial stiffness. To estimate pulmonary Arterial Compliance and Pulse Wave Velocity in Cerebral-Cardiovascular Patients using 64-Row Multi-Detector Computed Tomography Cardiac Images. Here in this work, we have used an in house developed three-dimensional reconstruction algorithm that extracts high-resolution cardiac Computer Tomography images in Digital Imaging and Communications in Medicine (DICOM) format from nine subjects. The subjects consist four patients with stroke (SR) turned to atrial fibrillation (AF) and five patients with both SR and AF. The calculation showed strok volume of Left and Right Ventricles, which are near equal to 62.56±12.61 ml and 65.95±13.13 ml, respectively, with a good positive correlation (R = 0.717, p < 0.0001) while pulse wave velocity and arterial compliance are calculated to be 0.21±0.0665 m/s and 0.09 ± 0.0547 ml/mmHg for patients with SR turned AF, 0.15±0.0502 m/s and 0.10 ± 0.0438 for the SR and AF patients. We concluded that the derived methodology for calculation of PWV and AC from 3D cardiac CT images could be used as an index in the evaluation of arterial stiffness.
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Hu et al. (2017) conducted an observational in Stroke and Atrial Fibrillation (n=9). 3D reconstruction algorithm from cardiac CT images was evaluated on Pulmonary Arterial Compliance, Pulse Wave Velocity, and Stroke Volume correlation (R = 0.717, p=< 0.0001). A 3D reconstruction algorithm from cardiac CT images estimated pulse wave velocity (0.21±0.0665 m/s) and arterial compliance (0.09±0.0547 ml/mmHg) in patients with stroke turned AF.
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