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Gastric syphilis is an uncommon disease, presenting nonspecific clinical and histological features.We present a rare case of 17-year-old women who had 2-week abdominal pain and sought for medical help.The patient was diagnosed with gastric syphilis, concomitantly infected with Helicobacter pylori (HP) and human immunodeficiency virus (HIV).The coexistence of HP and Treponema pallidum (TP) in gastric tissue was proved by immunohistochemical (IHC) staining.Multiple infections made diagnosis difficult.Comprehensive analysis of clinical, endoscopic, serological, and histopathologic data can avoid missed diagnosis.
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Zhang et al. (2020) studied this question.
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