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September 26, 2026Molecular MedicineOpen Access

SYK-dependent regulation of the AKT1/E-cadherin axis modulates invasion and migration in the Luminal A breast cancer

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Authors

JTJie TongLZLumeng ZhangWHWentong Hong

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Tong et al. (2026) studied this question.

synapsesocial.com/papers/6ab760235481e342659be7behttps://doi.org/10.1186/s10020-026-01649-4
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 333: Downregulation of AURKA and AURKB promotes a decrease in cell invasion in TNBC by modulating the expression of SNAIL1.2026
  2. 2Clinicopathogenomic analysis of AKT1-PIK3CA-PTEN-altered luminal metastatic breast cancer in Japan2024
  3. 3A PKM2-YAP reciprocal repartitioning modulates invasion of breast cancer cells2025
  4. 4CK2 targeting potentiates antineoplastic effects of dual HER2/EGFR inhibitor lapatinib and attenuates growth factor-induced epithelial-mesenchymal transition2026
  5. 5Data from AKT blocks SIK1-mediated repression of STAT3 to promote breast tumorigenesis2024