Key result
This protocol outlines a 12-month prospective observational study to evaluate the impact of macro-microcirculation coupling on clinical complications in head and neck surgery.
Observational
No
This protocol outlines an observational study to evaluate macro- and microcirculation coupling and its association with postoperative complications in head and neck oncological surgery.
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Bladder-catheter microcirculatory monitoring may complement macrohemodynamics in head-neck flap surgery; leaves open outcome impact in prospective studies.
(1) Background: Oncological demolitive-reconstructive surgeries in the head and neck region cause significant stress on patients' biohumoural, cardiac, and vascular systems, leading to disturbances in macrocirculatory and microcirculatory parameters. Traditional monitoring addresses the symptoms, but not the underlying cause. Microcirculatory assessments complement macrocirculatory monitoring, and bladder-catheter-based technology offers a better representation of central microcirculation. Flap reconstruction surgeries involve demolitive and reconstructive phases, requiring optimal tissue perfusion. The literature lacks a consensus on macro-microcirculation coupling, and there is no agreement on the use of vasopressors during head and neck surgeries. Evidence-based guidelines are lacking, resulting in variations in vasopressor administration. (2) Methods: This is a 12-month observational, prospective study conducted in a single center. It aims to evaluate the impact of macro-microcirculation coupling on clinical complications in head and neck surgery. All consecutive patients undergoing oncologic surgery requiring flap reconstruction and meeting the inclusion criteria will be enrolled. The study will utilize standard hemodynamic monitoring and bladder catheterization for measuring urine output and temperature. (3) Conclusions: The study aims to evaluate the coupling of macro- and microcirculation in head and neck surgeries, assess hemodynamic parameters and microcirculatory changes, and investigate their association with postoperative complications. The results can enhance patient care and surgical outcomes.
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Adembri et al. (2023) conducted an observational in Oncological demolitive-reconstructive head and neck surgery. Macro-microcirculation coupling was evaluated on Impact of macro-microcirculation coupling on clinical complications. This protocol outlines a 12-month prospective observational study to evaluate the impact of macro-microcirculation coupling on clinical complications in head and neck surgery.
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