Key result
Glucocorticoids and iron supplementation led to clinical and laboratory improvement in an 8-year-old girl with idiopathic pulmonary hemosiderosis presenting with recurrent iron-deficiency anemia.
Case Report (n=1)
Refractory or recurrent iron-deficiency anemia with pulmonary symptoms may be the only presenting feature of idiopathic pulmonary hemosiderosis in pediatric patients.
Consider IPH in refractory pediatric IDA with asthma; single case leaves open prospective validation.
Idiopathic pulmonary hemosiderosis (IPH) is a rare disorder with unknown pathogenesis that usually presents in the first decade of life. As a result of diffuse alveolar hemorrhage, respiratory symptoms such as cough attacks, hemoptysis, dyspnea, and recurrent and refractory iron-deficiency anemia (IDA) are observed. We present an 8-year-old girl who was followed up with recurrent IDA and allergic asthma and later diagnosed with IPH. IPH was confirmed by the presence of hemosiderin-laden macrophages in bronchoalveolar lavage obtained by bronchoscopy and exclusion of the secondary causes of pulmonary hemosiderosis. Glucocorticoids and iron supplementation were started. Clinical and laboratory improvement was observed with therapy. Our case illustrates that refractory/recurrent IDA with any pulmonary symptoms may be the only presenting feature of IPH.
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Eldem et al. (2015) conducted a case report in Idiopathic pulmonary hemosiderosis with allergic asthma and iron-deficiency anemia (n=1). Glucocorticoids and iron supplementation was evaluated on Clinical and laboratory improvement. Glucocorticoids and iron supplementation led to clinical and laboratory improvement in an 8-year-old girl with idiopathic pulmonary hemosiderosis presenting with recurrent iron-deficiency anemia.
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