The Location of the Positions of the Breakpoints Involved in the T26h and T70h Mouse Translocations With the AId of Giemsa-Banding

The positions of the breakpoints involved in the T(2;8)26H and T(1;13)70H mouse translocations have been located to specific minor bands using a trypsin-Giemsa banding method and a nomenclature system for band patterns as developed by Nesbitt and Francke (1973). The breakpoint positions are 2H1 and 8A4 for T26H and 1A4 and 13D1 for T70H. The interstitial segments occupy 80.9% of chromosome 2, 30.1% of chromosome 8, 14.4% of chromosome 1 and 88.0% of chromosome 13. It is concluded that the variation of the location of the breakpoint positions is mainly caused by differential chromosome contraction and measuring errors and only to a small extent by the resolving power of the G-banding technique.