Key result
Dysmetabolic syndrome traces to childhood, underscoring early pediatric screening and prevention needs.
Why the study?
The occurrence and characteristics of full-blown dysmetabolic syndrome in children and adolescents have only recently been investigated despite its known risk in adults.
Dysmetabolic syndrome has its origins in childhood, highlighting the need for effective screening and preventive strategies by pediatricians.
Supports childhood origins of dysmetabolic syndrome; leaves open optimal pediatric screening and prevention in prospective trials.
The dysmetabolic syndrome, consisting of dyslipidaemia, hypertension, hyperinsulinaemia and central obesity, has been well recognized as a major risk for cardiovascular disease in adults. Although the clustering of cardiovascular risk factors has also been identified in childhood, the occurrence of full-blown dysmetabolic syndrome at younger ages has only recently been investigated. In this article we attempted an overview of the data for children and adolescents, focused on the mechanisms and natural history of the disease, the prevalence among paediatric populations, the assessment and the treatment approaches. Conclusion: There is substantial evidence that the dysmetabolic syndrome has its origins in childhood. In the face of the epidemic increase of obesity in children and adolescents, the development of effective screening and preventive strategies would be a major challenge for paediatricians.
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Bitsori et al. (2005) conducted a review in Dysmetabolic syndrome. There is substantial evidence that the dysmetabolic syndrome has its origins in childhood, highlighting the need for effective screening and preventive strategies by pediatricians.
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