Key result
Asprosin protects cardiomyocytes against diabetes-related damage in preclinical models.
Why the study?
Diabetic cardiomyopathy is a major complication of diabetes mellitus leading to heart failure and death, and the role of asprosin in this context is not well understood.
Design
Other
Answers are grounded in this paper and cite their sources.
May warrant preclinical validation in diabetic cardiomyopathy models; leaves open any clinical relevance beyond cardiomyocyte studies.
Diabetic cardiomyopathy (DCM) is one of the most important independent complications of diabetes mellitus, which often lead to later-period heart failure and death. Asprosin is a new endogenous small molecular protein that plays an important role in glycolipid metabolism. However, information
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Feng et al. (2018) studied this question. Asprosin exerts a protective role against diabetes-related damage in cardiomyocytes.
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