Experimental study demonstrates lipid A remodeling in Antarctic Pseudomonas, indicating enhanced outer membrane fluidity and stability at near-zero temperatures.
sp. EW#7, a strain isolated from Enigma Lake in Antarctica where, among other extreme characteristics, water temperature can reach 0.4 °C. We show that near-zero growth temperature mostly affects the LPS lipid A component. An uncommon tendency of decreasing lipid A secondary hydroxylation while increasing its phosphorylation degree was observed. This resulted in a faster lateral diffusion of lipid chains in the membrane and therefore in an enhancement of its fluctuations that guarantee membrane integrity and flexibility.
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Mercogliano et al. (2024) studied this question.
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