Key result
Severe TAVI infective endocarditis with leaflet degeneration necessitates surgical replacement at 1 year.
Why the study?
Early degeneration and infective endocarditis of transcatheter heart valves in patients with autoimmune disorders treated with corticosteroids require detailed characterization.
Population
1 83-year-old woman with multiple autoimmune disorders treated with corticosteroids after trans-aortic valve implantation
Comparison
Surgical aortic valve replacement following 2 weeks of antibiotic treatment
Design
Case report
Follow-up
Until hospital discharge
Authors
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Raises awareness of late TAVI endocarditis with degeneration; leaves open incidence, risk factors, and surveillance needs.
Case Report (n=1)
This case demonstrates that early massive structural degeneration and infective endocarditis can occur in transcatheter heart valves, potentially exacerbated by autoimmune conditions and immunosuppression.
Spartera et al. (2016) conducted a case report in Infective endocarditis and early degeneration of a transcatheter heart valve (n=1). Transcatheter aortic valve implantation (23-mm Edward Sapien 3) was evaluated. An 83-year-old woman developed infective endocarditis and massive prosthetic leaflet degeneration one year after transcatheter aortic valve implantation, requiring surgical replacement.
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