Key result
Continuing DAPT during simple dental extraction shows no increase in bleeding risk vs. discontinuation.
Why the study?
Altered platelet function and increased bleeding time can occur with antiplatelet therapy, and the need to stop dual antiplatelet therapy before dental extraction was evaluated.
Does continuation of dual antiplatelet therapy increase bleeding risk in patients undergoing simple dental extractions compared to discontinuation?
Cohort (n=150)
Does continuation of dual antiplatelet therapy increase bleeding risk in patients undergoing simple dental extractions compared to discontinuation?
Absolute Event Rate: 0% vs 0%
Continuing dual antiplatelet therapy during simple dental extractions does not significantly increase bleeding risk compared to stopping therapy 1 week prior.
Supports continuing DAPT during simple dental extractions without excess bleeding; hypothesis-generating and requires randomized confirmation.
Aims and Objectives: Altered platelet function and increased bleeding time (BT) can occur with antiplatelet therapy. This study was conducted to evaluate the need for stoppage of dual antiplatelet therapy in patients undergoing dental extractions. Materials and Methods: One hundred and fifty patients indicated for dental extraction were grouped as Group I: Consisted of 75 patients on dual antiplatelet therapy and Group II: Consisted of 75 patients who have discontinued antiplatelet therapy 1 week before dental extraction. BT of all the participants was recorded before extraction procedures. Under local anesthesia, single molar tooth indicated for simple extraction was done in both the groups. Suturing along with pressure pack was done after extraction. BT after extraction was statistically checked between the groups after 1 h and 24 h using Chi-square test with P < 0.05. Results: Postoperatively, none of the patients in both the groups showed active bleeding 1 h and 24 h. No bleeding was seen in 73 patients in Group I and 78 patients in Group II after 24 h. Conclusion: This study concluded that there is no significant difference in BT in both the groups. Antiplatelet monotherapy or even antiplatelet dual therapy needs no alteration or stopped before minor oral surgical procedures. Most of the postoperative bleeding can be easily controlled by local hemostatic measures.
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Babaji et al. (2018) conducted a cohort in Dental extraction on dual antiplatelet therapy (n=150). Continuation of dual antiplatelet therapy vs. Discontinuation of antiplatelet therapy 1 week before extraction was evaluated on Active bleeding at 1 h and 24 h. Continuation of dual antiplatelet therapy during simple dental extraction resulted in no active bleeding at 1 and 24 hours (0%), showing no significant difference compared to discontinuation.
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