Key result
Visuospatial tasks increase right over left MCA peak blood flow velocity by ~4% on fTCD.
Why the study?
The ability of functional transcranial Doppler sonography (fTCD) to detect hemispheric lateralization and its validation against functional MRI (fMRI) was investigated.
Can functional transcranial Doppler sonography (fTCD) reliably detect cognitive hemispheric lateralization compared to functional MRI (fMRI) in healthy subjects?
Population
14 healthy, right-handed subjects
Comparison
Functional transcranial Doppler sonography vs functional MRI during visuospatial task
Design
Cross-sectional study
Authors
Loading...
May support fTCD for detecting visuospatial lateralization; leaves open clinical reliability versus fMRI.
Cross-Sectional (n=14)
Can functional transcranial Doppler sonography (fTCD) reliably detect cognitive hemispheric lateralization compared to functional MRI (fMRI) in healthy subjects?
Absolute Event Rate: 111.3% vs 107.1%
p-value: p=<0.05
Functional transcranial Doppler sonography can reliably detect cognitive hemispheric lateralization, cross-validated by functional MRI.
Knecht et al. (1999) conducted a cross-sectional in Healthy (n=14). Functional transcranial Doppler sonography (fTCD) vs. Functional MRI (fMRI) was evaluated on Mean peak blood flow velocity increase (right vs left MCA) (p=<0.05). Functional transcranial Doppler sonography detected a higher mean peak blood flow velocity increase in the right MCA (111.3%) versus the left MCA (107.1%, P<0.05) during a visuospatial task.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: