Key result
Supravalvular aortic stenosis is associated with an ~18 mm Hg interarm systolic blood pressure difference.
Why the study?
The mechanism underlying unequal upper extremity blood pressures in patients with supravalvular aortic stenosis was unclear.
Does the Coanda effect explain asymmetric upper extremity blood pressures in patients with supravalvular aortic stenosis compared to valvular aortic stenosis?
Observational (n=76)
Does the Coanda effect explain asymmetric upper extremity blood pressures in patients with supravalvular aortic stenosis compared to valvular aortic stenosis?
Answers are grounded in this paper and cite their sources.
The Coanda effect explains the disproportionately high right arm blood pressure in supravalvular aortic stenosis, as the smooth annular narrowing conserves jet stream kinetic energy along the right aortic wall.
The Coanda effect, the tendency of a jet stream to adhere to a wall, was investigated as an explanation of the unequal pressures in the upper extremities in patients with supravalvular aortic stenosis (SVAS). Of 56 patients with SVAS reviewed, 48 had unequal blood pressures in the upper extremities. The average difference was 18 mm Hg systolic. Although 11 of the 20 patients in the control group (valvular aortic stenosis) had some blood pressure asymmetry, the average difference was 3.5 mm Hg systolic. In valvular aortic stenosis, the velocity of the jet is quickly dissipated beyond the stenotic orifice, preventing any sustained high-velocity stream. However, the smooth, annular narrowing of SVAS creates a "step" between the orifice and the ascending aortic wall which enhances the natural affinity of a jet for a boundary wall and conserves the kinetic energy of the jet stream. In most patients with SVAS, the high-velocity stream is along the right aortic wall, causing disproportionately high pressure in the right arm.
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French et al. (1970) conducted an observational in Supravalvular aortic stenosis (n=76). Supravalvular aortic stenosis vs. Valvular aortic stenosis was evaluated on Average systolic blood pressure difference between upper extremities. Supravalvular aortic stenosis was associated with a higher average systolic blood pressure difference between upper extremities (18 mm Hg) compared to valvular aortic stenosis (3.5 mm Hg).
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