Using a laser monitoring observation technique, we determined the solubilities of paroxetine hydrochloride hemihydrate in N, N -dimethylformamide, methyl isobutyl ketone, tetrahydrofuran, ethyl acetate, methanol, ethanol, 1-propanol, 1-butanol, and 2-butanol by the synthetic method from 286 K to 363 K. Results of these measurements were correlated by an empirical equation.
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Ren et al. (2004) studied this question.
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