Key result
Sudden cardiac arrest accounts for ~25% of all-cause mortality in chronic dialysis patients.
Why the study?
Death from cardiovascular disease and sudden cardiac arrest are major causes of mortality in chronic dialysis patients, with poor survival after cardiac arrest and a need for prevention strategies.
This review highlights the extraordinarily high risk of sudden cardiac arrest in dialysis patients and discusses potential preventive strategies.
SCA causes 25% of deaths on dialysis; leaves open whether blood purification alters this risk.
Death from cardiovascular disease in general and sudden cardiac arrest (SCA) in particular are exponentially proportional to declining renal function and are a major cause of mortality among those with chronic kidney disease (CKD). The greatest risk, however, is reserved for those patients on chronic dialysis. These individuals have an extraordinarily high rate of death, with cardiac disease accounting for 45% and SCA responsible for 25% of all-cause mortality. Once cardiac arrest occurs, survival is extremely poor. Thus, reducing mortality from cardiovascular disease and SCA in dialysis patients is a global health challenge. The main objectives of this review are to elucidate the nature of SCA in the dialysis population, describe possible mechanisms and risk factors, and discuss options for prevention.
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ROD S. PASSMAN (2013) conducted a review in Chronic dialysis. Sudden cardiac arrest accounts for 25% of all-cause mortality in chronic dialysis patients, highlighting the need for effective prevention strategies such as drugs and defibrillators.
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