Pathogenicity of local identified NDV strain related to genotype VII to 28 day old commercial broiler chickens

Twenty five broiler chicks were days old chicken were infected by oculonasal route each with of EID of local identified NDV local isolate NDV chicken EG QU NRC Clinical signs begin at the nd dpi and at the rd dpi marked depression with sleepy appearance severe respiratory signs and marked decrease in feed intake greenish lose dropping beasty vent with greenish diarrhea sudden high mortalities with death of birds in rate of At the th and th dpi same severe signs where greenish diarrhea was obvious with respiratory sounds were detected with death of birds in each At th dpi death of bird The morbidity rate was while mortalities reach in days Post mortem examination of dead chickens in the infected group showed congested muscles dehydrated anorexic bird hemorrhages on the tips of periventricular glands liver congestion greenish intestinal contents greenish content of proventriculus and gizzard severe necrosis and ulceration on cecal tonsils and catarrhal tracheitis NDV cloacal shedding was detected in cloacal swabs from infected chickens at and dpi by RT PCR Histopathological examination reveals the detection of showing necrosis of intestinal villi hemorrhage and lymphocytic infiltration in intestinal sections Cecal tonsils showed lymphocytic necrosis with areas of hemorrhage Trachea showing Necrosis of lamina epithelialis edema and hemorrhage in submucosa Severe hemorrhage with severe lymphocytic depletion in spleen