Biological effect of alpha-Lipoic Acid on Aflatoxicosis in Broiler chickens

Aflatoxicosis, is still unresolved problem in poultry production caused severe economic losses due to it reduces immunity, damages different tissues, reduces carcass quality and increases susceptibility to infectious diseases, so this work aimed to determine the ability of lipoic acid (universal antioxidant) to ameliorate the harmful effects of aflatoxins in broiler chickens as alternative feed additives and to detect its effect on performance, liver & kidney function, antioxidant status andhistopathological changes.125one-day old commercial chicks reared under strict hygienic measures and fed basal diet till 8th day of age then 5 chicks were slaughtered and their serum samples were obtained while other 120 chicks were divided into 4 equal groups (n=30),each group subdivided into 3 replicates (10 birds/replicate).Group 1: fed a basal diet (control).Group 2:lipoic acid treated, Group 3:aflatoxicated.Group