Key result
Radiofrequency ablation successfully terminates post-transplant atrial fibrillation driven by recipient-to-donor electrical connections.
Why the study?
Atrial tachyarrhythmia originating from the recipient heart and propagating through recipient-to-donor atrio-atrial connections post heart transplant is rare and mostly reported years after transplant.
Case Report (n=1)
Atrio-atrial connections between recipient and donor can form as early as a few months post heart transplant, and radiofrequency ablation is an effective treatment for resulting atrial fibrillation.
May support ablation for post-transplant AF via atrio-atrial connections; hypothesis-generating and requires prospective validation.
INTRODUCTION: Atrial fibrillation and atrial flutter originating from the donor s heart is a commonly reported complication post heart transplant. Atrial tachyarrhythmia originating from the recipient s heart, propagated through recipient-to-donor connections, is rare with only few cases reported in the literature; most reported cases from our review occur years post-transplant. CASE: A 47-year-old male presented with atrial tachycardia 6 months post heart transplant. Electrophysiologic study demonstrated atrial fibrillation originating from native heart and propagated through atrio-atrial connections to the donor heart. This arrhythmia was successfully terminated with radiofrequency ablation. CONCLUSION: Atrio-atrial connection between recipient and donor can form as early as a few months post heart transplant. Radiofrequency ablation appears to be an effective treatment for atrial fibrillation propagated through donor-to-recipient connections.
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Izekor et al. (2024) conducted a case report in Atrial tachycardia post heart transplant (n=1). Radiofrequency ablation was evaluated on Termination of arrhythmia. Radiofrequency ablation successfully terminated atrial fibrillation propagated through recipient-to-donor connections 6 months post heart transplant.
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