A green perspective: Synthesis of 2-chloro-3-formylquinolines and its derivatives

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This review summarizes the green synthetic methods and reactions of 2-chloroquinoline-3-carbaldehydes. The reactions are subdivided in groups on the basis of which type of method used, that is, microwave, ultrasound, and grinding/solvent free/water as solvent. Most reaction types have been successfully applied and used in the production of biological active compounds.