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January 10, 2002Chemical Communications

Lipophilic derivatives of cyclam as new inhibitors of tumor cell growth

John W. Sibert Ann H. Cory Joseph G. Cory

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Abstract

Two new lipophilic tetraazamacrocycles were prepared and, in contrast to non-lipophilic analogs, found to be potent inhibitors of tumor cell growth in vitro with IC50 values below 10 micromolar.

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Sibert et al. (2002) studied this question.

synapsesocial.com/papers/6ab8b4164df4b4376c330082 https://doi.org/10.1039/b107899m

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