Key result
In 58 children with heart failure, the main aetiologies were congenital heart disease (35%), renal hypertensive disease (26%), rheumatic heart disease (17%), and cardiomyopathies (12%).
Why the study?
The aetiology of congestive cardiac failure in children with suspected structural abnormalities in southwestern Uganda was not well described.
What is the aetiology of congestive cardiac failure in children presenting to a regional hospital in Uganda?
Observational (n=58)
No
What is the aetiology of congestive cardiac failure in children presenting to a regional hospital in Uganda?
This study highlights the ongoing prevalence of congenital and rheumatic heart disease, as well as a significant new finding of renal hypertension as a cause of heart failure in Ugandan children.
Answers are grounded in this paper and cite their sources.
Informs diagnostic evaluation of heart failure in Ugandan children; hypothesis-generating for regional prevention strategies.
The aim of this study was to describe the aetiology of congestive cardiac failure (CCF) in children with suspected structural abnormalities presenting to a regional hospital in southwestern Uganda. The method used was a prospective descriptive study of successive admissions of children with persistent cardiac signs after routine treatment of CCF. Children with severe anaemia (haemoglobin [Hb]<7 g/dL), pneumonia, sepsis or severe malnutrition were excluded. Chest X-ray, electrocardiogram and echocardiography data were validated by a paediatric cardiologist and radiologist at the Bristol Royal Hospital for Children, UK. A cohort of 58 patients was identified. The aetiology of heart failure in this cohort (n = 58) was due to congenital heart disease (35%), renal hypertensive disease (26%), rheumatic heart disease (17%), cardiomyopathies (12%), endomyocardial fibrosis (7%) and tamponade (3%). In conclusion, this study confirmed the ongoing prevalence of congenital heart disease, rheumatic heart disease and endomyocardial fibrosis in this area. The cardiac effect of renal hypertension was a new and significant finding.
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Ellis et al. (2007) conducted an observational in Congestive cardiac failure (CCF) (n=58). Aetiology of congestive cardiac failure was evaluated on Aetiology of heart failure. In 58 children with heart failure, the main aetiologies were congenital heart disease (35%), renal hypertensive disease (26%), rheumatic heart disease (17%), and cardiomyopathies (12%).
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