Key result
Surgical resection of a dedifferentiated liposarcoma temporarily resolved severe leukocytosis (from 103,700/μl to 6,920/μl) and elevated serum G-CSF levels (from 620 pg/ml to 12 pg/ml).
Population
72-year-old man with dedifferentiated liposarcoma arising from his upper arm, presenting with leukocytosis.
Design
Case_report
Follow-up
3 months
Authors
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May indicate G-CSF-driven leukocytosis in dedifferentiated liposarcoma; hypothesis-generating and should not yet change practice.
Case Report (n=1)
No
This case report suggests a possible association between G-CSF-producing soft-tissue tumors and an undifferentiated liposarcoma lineage.
Sakamoto et al. (2007) conducted a case report in Dedifferentiated liposarcoma with leukocytosis (n=1). Surgical resection was evaluated on White blood cell count and serum G-CSF levels. Surgical resection of a dedifferentiated liposarcoma temporarily resolved severe leukocytosis (from 103,700/μl to 6,920/μl) and elevated serum G-CSF levels (from 620 pg/ml to 12 pg/ml).
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