Key result
Higher preoperative LA reservoir strain is linked to ~73% lower POAF risk after CABG.
Why the study?
Postoperative atrial fibrillation is a common complication after CABG with significant morbidity and mortality, and the value of preoperative LA strain measurement for risk prediction is unclear.
Does preoperative left atrial strain measurement predict postoperative atrial fibrillation in patients undergoing isolated CABG?
Cohort (n=100)
Does preoperative left atrial strain measurement predict postoperative atrial fibrillation in patients undergoing isolated CABG?
Odds Ratio: 0.27
p-value: p=0.02
Preoperative left atrial strain measurements offer added value in predicting the risk of postoperative atrial fibrillation in patients undergoing CABG.
Preoperative LA strain may refine POAF risk assessment after CABG; leaves open whether it should guide prophylaxis or change practice.
AIM: Postoperative Atrial Fibrillation (POAF) is a common complication following Coronary Artery Bypass Grafting (CABG), associated with increased morbidity and mortality. Aim of the study is to analyze whether the measurement of preoperative Left Atrial (LA) strain can offer advantages over conventional clinical and echocardiographic parameters to identify patients at risk of developing POAF. METHODS AND RESULTS: We conducted a prospective study involving 100 patients undergoing isolated CABG from April 2023 to April 2024. Key parameters measured included LA strain measurements, Left Atrial Emptying Fraction (LA-EF), Left Ventricular Ejection Fraction, Left Atrial Volume index (LAVi). POAF occurred in 27 patients (27 %) with a mean latency of 3.2 ± 2.1 days. Higher preoperative serum creatinine levels were significantly associated with POAF. LA strain parameters (LA Reservoir Strain, LA Contraction Strain) and LA-EF were all significantly lower in the POAF group. Multivariate logistic regression identified LA Contraction Strain (OR: 0.73, p = 0.04), LA Reservoir Strain (OR: 0.27, p = 0.02) and preoperative serum creatinine (OR: 0.55, p = 0.01) as significant predictors of POAF. ROC curve analysis indicated that LA Reservoir Strain ≤24.5 %, LA Contraction Strain ≤9.5 %, LA-EF ≤ 43.4 % have a good accuracy in detection of POAF. Significant correlations were found between LAVi and LA Reservoir Strain, LAVi and LA-EF, and LA Reservoir Strain and LA-EF. CONCLUSIONS: Preoperative LA analysis are significant predictors of POAF. These findings suggest that echocardiographic strain measurements offer an added value in preoperative risk assessment for POAF in CABG patients.
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Granchietti et al. (2025) conducted a cohort in Postoperative Atrial Fibrillation after Coronary Artery Bypass Grafting (n=100). Preoperative Left Atrial (LA) strain was evaluated on Postoperative Atrial Fibrillation (POAF) (OR 0.27, p=0.02). Lower preoperative left atrial reservoir strain (OR 0.27, p=0.02) and contraction strain (OR 0.73, p=0.04) significantly predicted postoperative atrial fibrillation after isolated CABG.
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