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(Abstracted from N Engl J Med 2016;375:1–4) During an outbreak in 2013–2014, the rate of Zika virus (ZIKV) infection in the Polynesian population was estimated at a rate of 66%, and it was estimated that it posed a risk of microcephaly in the first trimester of pregnancy of 0.95% (95% confidence interval [CI], 0.34%–1.91%). In order to estimate the risk of microcephaly in the recent Brazilian outbreak, where Zika infection rates are not known, a range of 10% to 80% of ZIKV infection rates were estimated in Bahia.
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Johansson et al. (2016) studied this question.
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