Reversible and pH‐Sensitive Vesicles from Amphiphilic Homopolymer Poly(2‐(4‐vinylphenyl)pyridine)

The sigma bond between the 2-phenyl pyridine head groups and the vinyl backbone of poly(2-(4-vinylphenyl)pyridine) allows for free rotation of the head groups in response to the polymer's environment (see image) and the hydrophobic vinyl backbone provides curvature for the formation of bilayer vesicles with a 1-nm membrane thickness. The homopolymer vesicles act as a reservoir for both hydrophobic and hydrophilic molecules, individually or simultaneously.