Key result
Staphylococcus aureus infective endocarditis causes fatal cerebral thrombosis in a healthy 6-year-old child.
Why the study?
Infective endocarditis is rare in children and typically associated with underlying heart disease or dental procedures, but cases without these risk factors are less described.
Case Report (n=1)
Highlights that fatal Staphylococcus aureus infective endocarditis can occur in children without underlying structural heart disease or recent dental procedures.
Infective endocarditis is rare in children but can cause significant morbidity and mortality.Streptococcus and Staphylococcus species are the leading causes of this disease.Staphylococcus is more common in people with underlying heart disease, and Streptococcus viridans is more common in people who have had a dental procedure.In general, any fever of unknown origin in children with an underlying heart problem should be carefully evaluated for endocarditis, and empiric therapy should be performed.The main symptoms of the disease include fever, new murmur, deterioration of the previous murmur, hematuria, embolic events, splenomegaly, bleeding splinter, Osler's nodes, Janeway lesion, and Roth spots.One of the important complications of infective endocarditis is cerebrovascular event and stroke.Herein, we describe a 6-yearold girl presented with fever and skin lesions and no history of underlying heart problem or dental procedure.The patient expired after three days of mitral valve infection with S. aureus.
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A 2021 study conducted a case report in Infective endocarditis (n=1). Staphylococcus aureus infection was evaluated on Clinical outcome. A 6-year-old girl with no underlying heart or dental problems developed infective endocarditis caused by Staphylococcus aureus and expired after three days due to severe complications including cerebral thrombosis.
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