Characteristics of Children Hospitalized With Infective Endocarditis
Key result
Pediatric infective endocarditis was associated with a 5% overall in-hospital mortality rate, with Staphylococcus aureus being the most common causative organism (57%).
Population
1,588 hospitalizations of patients <21 years of age with infective endocarditis from a national sample.
Design
Cohort
Follow-up
In-hospital
Authors
Discussion
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Member takes
Implication
May guide empiric anti-staphylococcal therapy in suspected pediatric IE; leaves open optimal strategies amid shifting demographics.
Study Design
Type
Observational (n=1,588)
Multicenter
Yes
Structured PICO
P
Population
1,588 hospitalizations for infective endocarditis among patients <21 years of age from a large national database in 2000 and 2003.
O
Outcome
Clinical characteristics, causative organisms, and in-hospital mortalityhard clinical
The epidemiology of pediatric infective endocarditis shows a shift toward children without preexisting heart disease, with S. aureus as the most common organism and a 5% in-hospital mortality rate.
Cite This Study
Gauvreau et al. (2009) conducted an observational in Infective endocarditis (n=1,588). Infective endocarditis was evaluated on In-hospital mortality. Pediatric infective endocarditis was associated with a 5% overall in-hospital mortality rate, with Staphylococcus aureus being the most common causative organism (57%).