Recent data suggest that fever may be initiated by products of liver macrophages that activate subdiaphragmatic vagal afferents. In the brain, these inputs may be transmitted to fever-producing sites via noradrenergic pathways;prostaglandin E2 may be the ultimate pyrogenic mediator.
No takes yet. Share an insight, caveat, or question.
Cm et al. (1997) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: