Key result
Double-oblique cine MRI identifies bicuspid aortic valves with ~97% diagnostic accuracy.
Why the study?
The diagnostic accuracy of double-oblique SSFP cine MRI in distinguishing normal and bicuspid aortic valves was assessed to determine its sensitivity and specificity.
Does double-oblique SSFP cine MRI accurately distinguish between normal and bicuspid aortic valves in patients referred for cardiac MRI?
Population
38 patients referred for MRI of the heart and thoracic aorta including 17 with bicuspid aortic valve and 21 controls
Comparison
Double-oblique SSFP cine MRI assessment vs echocardiography reference standard
Design
Retrospective case-control study with blinded independent assessment by two radiologists
Authors
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May aid bicuspid valve detection on cardiac MRI referrals; hypothesis-generating and requires prospective validation before practice change.
Case-Control (n=38)
Blinded
Does double-oblique SSFP cine MRI accurately distinguish between normal and bicuspid aortic valves in patients referred for cardiac MRI?
Double-oblique SSFP cine MRI provides excellent diagnostic accuracy, with 100% sensitivity and 95% specificity, for distinguishing bicuspid from normal aortic valves.
Gleeson et al. (2008) conducted a case-control in Bicuspid aortic valve (n=38). Double-oblique steady-state free-precession (SSFP) cine MRI vs. Normal aortic valve (controls) was evaluated on Diagnostic sensitivity and specificity in distinguishing normal and bicuspid aortic valves. Double-oblique SSFP cine MRI demonstrated 100% sensitivity and 95.2% specificity in distinguishing bicuspid from normal aortic valves, with an overall diagnostic accuracy of 97.36%.
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