Key result
Statins emerge as promising neuroprotective therapies targeting inflammation and apoptosis in perinatal stroke.
Why the study?
Perinatal stroke causes severe lifelong neurological deficits and there is a need to explore potential pharmacological treatments to reduce ischemic damage.
Population
Term births, infants, children, and animal models with perinatal stroke
Comparison
Pharmacological treatments targeting inflammatory process and apoptotic cell death, including statins
Design
Review article
Authors
Loading...
Should not change perinatal stroke management; hypothesis-generating for statin neuroprotection and requires prospective trials.
Statins and other pharmacological treatments targeting inflammation and apoptosis represent emerging therapeutic strategies for neuroprotection in perinatal stroke.
Balduini et al. (2004) conducted a review in Perinatal stroke. Pharmacological treatments (statins) was evaluated. Pharmacological treatments targeting inflammation and apoptosis, particularly statins, are emerging as potential neuroprotective strategies for perinatal stroke.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: