Partial Glossectomy for Treatment of Macroglossia Secondary to Myeloma-Associated Amyloidosis: A Case Report

Around 10-15% of patients with multiple myeloma develop amyloidosis due to the extracellular deposition of light-chain amyloid molecules.When this deposition occurs in the tongue, patients may exhibit macroglossia.The sequelae of this macroglossia can include dysphagia and gagging, tooth displacement, and airway compromise.This article presents the case of a 43-year-old African American female who was treated with a partial glossectomy secondary to amyloidosis related multiple myeloma.