Key result
Remimazolam provides stable hemodynamics during TAVI in severe aortic stenosis case series.
Why the study?
Maintaining hemodynamic stability during general anesthesia for TAVI in patients with severe aortic stenosis is crucial, and the safety of remimazolam for this purpose was assessed.
Does remimazolam maintain hemodynamic stability during general anesthesia for TAVI in patients with severe aortic stenosis?
Case Report (n=7)
Does remimazolam maintain hemodynamic stability during general anesthesia for TAVI in patients with severe aortic stenosis?
Remimazolam appears safe and effective for maintaining hemodynamic stability during induction and maintenance of general anesthesia for TAVI in patients with severe aortic stenosis.
May support remimazolam in severe-AS TAVI; hypothesis-generating and should not yet change practice.
Background and Objectives: In patients with severe aortic stenosis (sAS), it is crucial to maintain hemodynamic stability during the induction and maintenance of general anesthesia for transcatheter aortic valve implantation (TAVI). In this study, we assessed the efficacy and safety of remimazolam in maintaining hemodynamic stability during anesthetic induction and maintenance. Cases: TAVI was performed on seven patients with sAS, and remimazolam was administered for total intravenous anesthesia (TIVA) of general anesthesia with induction (3.0 mg/kg/h) and maintenance (1.0 mg/kg/h). All patients underwent TAVI without major hemodynamic concerns and later recovered. Conclusions: Remimazolam can be safely used for induction and maintenance of general anesthesia in patients with sAS when performing TAVI.
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Kim et al. (2022) conducted a case report in Severe aortic stenosis (n=7). Remimazolam was evaluated on Hemodynamic stability during anesthetic induction and maintenance. Remimazolam for total intravenous anesthesia allowed 7 patients with severe aortic stenosis to undergo TAVI without major hemodynamic concerns.
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